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The psychological aspects of degenerative diseases of the central nervous system.
Vargová, Helena ; Šivicová, Gabriela (advisor) ; Kaplan, Cyril (referee)
The degenerative diseases affect not only the central nervous system, but also attacks neurological, mainly motoric, functions. These diseases undoubtedly influence mental functions as well. In the theoretical part, the thesis focuses on a possible correlation between the psychical disposition - mainly emotional, and its influence on the development or progression of this kind of disease. Furthermore, the thesis concentrates on the cognitive alternations accompanying given diseases, on the patients' behavioral changes and emotional alternation. The thesis also presents coping strategies and recommendations concerned with the issue of degenerative diseases of CNS based on the recent studies. A research proposal in the empirical part focuses on the effects of social support and coping strategies on the patient with ALS disease and it also explores the patients' motivation and potential future goals which interfere with the quality of life. Powered by TCPDF (www.tcpdf.org)
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Changes in neuroglia in degenerative disorders of the central nervous system
Kirdajová, Denisa ; Zach, Petr (advisor) ; Hock, Miroslav (referee)
Neurodegenerative diseases are a serious disorders of the central nervous system characterized by neuronal loss with a subsequent damage of the brain. This damage may have diverse consequences like a gradual loss of memory and intellect, problems with musculoskeletal system and not least death. Causes of these diseases are not yet fully understood. In addition to neurons neuroglia also plays an important role in these diseases of the central nervous system. In neurodegenerative diseases are astrocytes, oligodendrocytes, microglia and NG2 cells involved in their many aspects. They participate in the protective as well as in the detrimental aspect of these diseases. This work, therefore, presents an overview of previously acquired knowledge of neuroglia in various types of degenerative disorders of the CNS (Alzheimer`s disease, Parkinson`s disease, amyotrophic lateral sclerosis, multiple sclerosis, Wernicke encephalopathy, HIV associated dementia, frontotemporal dementia, vascular dementia). Powered by TCPDF (www.tcpdf.org)
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